Objective: To observe the therapeutic effect of Tibetan Tea combined with atorvastatin calcium in treating hyperlipidemia, 80 patients with hyperlipidemia were randomly divided into an experimental group and a control group of 40 each. The experimental group was treated with Tibetan tea combined with atorvastatin calcium, while the control group received only atorvastatin calcium. Changes in lipid levels, body composition measurements (body weight, body fat percentage, body mass index [BMI], waist circumference, visceral fat area), serum oxidative stress indicators [superoxide dismutase (SOD), malondialdehyde (MDA)], and Insulin resistance monitoring indicators [serum insulin, serum free fatty acids (FFA), homeostasis model assessment for insulin resistance (HOMA-IR)] after 12 weeks of treatment were observed.
Results: Compared to before treatment, the experimental group showed significantly reduced body weight, BMI, body fat percentage, waist circumference, visceral fat area, HOMA-IR, serum FFA, and MDA, as well as a significant increase in serum SOD. Compared to the control group, the experimental group had a significantly lower body fat percentage, body weight, waist circumference, visceral fat area, serum FFA, and MDA, as well as a significant increase in serum SOD. Clinical trials demonstrated that the combination of Tibetan tea and atorvastatin calcium is more effective in lowering lipids, reducing visceral fat, and improving insulin resistance and oxidative stress levels in patients with hyperlipidemia.
Keywords: Tibetan tea; hyperlipidemia; visceral fat; free fatty acids; oxidative stress
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Hyperlipidemia refers to a condition where triglycerides (TG), cholesterol (CHOL), and low-density lipoprotein (LDL) levels in the serum exceed normal standards, or high-density lipoprotein (HDL) levels are abnormally low. This is a common clinical disease characterized by dyslipidemia that can lead to damage in multiple organs and is a risk factor for various diseases such as coronary heart disease, diabetes, chronic kidney disease, and stroke, severely impacting quality of life and health. Early detection of hyperlipidemia and timely intervention are crucial for reducing the occurrence and development of cardiovascular and cerebrovascular diseases and chronic kidney disease. The foundation for preventing and treating hyperlipidemia lies in a healthy lifestyle and dietary interventions.
Tea, Coffee, and cocoa are the world's three major non-alcoholic beverages. Among them, tea is widely consumed due to its good health benefits. In recent years, studies on the health benefits of Tibetan tea and its active components have garnered considerable attention. Both in vitro cell experiments and animal model studies have confirmed the potential preventive and therapeutic effects of Tibetan tea and its active components on high Blood sugar, Hypertension, and hyperlipidemia. However, current research on the lipid-lowering and weight-reducing effects of Tibetan tea mostly involves animal experiments or observational studies in humans. Therefore, this study aimed to conduct a randomized controlled trial to explore the efficacy of drinking Tibetan tea in patients with hyperlipidemia and its possible mechanisms.
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